prikaz prve stranice dokumenta Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima
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master's thesis
Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima
2022. urn:nbn:hr:168:493409
Yatsukha, Roman
University of Zagreb
Faculty of Electrical Engineering and Computing

Cite this document

Yatsukha, R. (2022). Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima (Master's thesis). Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing. Retrieved from https://urn.nsk.hr/urn:nbn:hr:168:493409

Yatsukha, Roman. "Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima." Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2022. https://urn.nsk.hr/urn:nbn:hr:168:493409

Yatsukha, Roman. "Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima." Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2022. https://urn.nsk.hr/urn:nbn:hr:168:493409

Yatsukha, R. (2022). 'Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima', Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, accessed 14 November 2024, https://urn.nsk.hr/urn:nbn:hr:168:493409

Yatsukha R. Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima [Master's thesis]. Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing; 2022 [cited 2024 November 14] Available at: https://urn.nsk.hr/urn:nbn:hr:168:493409

R. Yatsukha, "Metoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima", Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:168:493409

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Metadata
TitleMetoda za sastavljanje genoma temeljena na De Bruijn grafovima i minimizatorima
Title (english)Minimizer-based de Bruijn Graph De Novo Assembler
AuthorRoman Yatsukha
MentorMile Šikić (mentor)
Committee memberMile Šikić (predsjednik povjerenstva)
Committee memberMirjana Domazet-Lošo (član povjerenstva)
Committee memberKrešimir Križanović (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Electrical Engineering and Computing
Zagreb
Defense date and country2022-07-01, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Computing
Abstract
Cpp-mdbg je efikasan asembler genoma koji sastavlja de Bruijn graf u prostoru "minimizera". Koristeći pažljivo odabrane parametre, graf se sastavlja iz rijetkih reprezentacija sekvenci u prostoru minimizera, što rezultira kompaktnim grafom koji se može brzo obraditi. U ovom radu demonstriramo kako je moguće sastaviti ljudski genom po uzoru na CHM13 ispod 20 minuta s pokrivenošću od preko 99%. Asembler podržava razrješavanje haplotipa koristeći trio binning.
Abstract (english)
Cpp-mdbg is an efficient genome assembler that uses minimizer based de Bruijn graphs. Using carefully picked parameters, the graph is assembled from sequences sparsely represented by minimizers, which results in a compact, easy to process graph. In this work we assemble a human genome inspired by CHM13 under 20 minutes with over 99% bases of the reference genome covered. The assembler supports haplotype resolution using trio binning.
Keywords
Keywords (english)
Languageenglish
URN:NBNurn:nbn:hr:168:493409
Study programmeTitle: Computing
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka računarstva (magistar/magistra inženjer/inženjerka računarstva)
Type of resourceText
File originBorn digital
Access conditionsClosed access
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Created on2023-01-14 10:17:38