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master's thesis
Preklapanje visoko pouzdanih jednomolekularnih očitanja
2020. urn:nbn:hr:168:619320
Babojelić, Dario
University of Zagreb
Faculty of Electrical Engineering and Computing

Cite this document

Babojelić, D. (2020). Preklapanje visoko pouzdanih jednomolekularnih očitanja (Master's thesis). Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing. Retrieved from https://urn.nsk.hr/urn:nbn:hr:168:619320

Babojelić, Dario. "Preklapanje visoko pouzdanih jednomolekularnih očitanja." Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2020. https://urn.nsk.hr/urn:nbn:hr:168:619320

Babojelić, Dario. "Preklapanje visoko pouzdanih jednomolekularnih očitanja." Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2020. https://urn.nsk.hr/urn:nbn:hr:168:619320

Babojelić, D. (2020). 'Preklapanje visoko pouzdanih jednomolekularnih očitanja', Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, accessed 17 April 2024, https://urn.nsk.hr/urn:nbn:hr:168:619320

Babojelić D. Preklapanje visoko pouzdanih jednomolekularnih očitanja [Master's thesis]. Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing; 2020 [cited 2024 April 17] Available at: https://urn.nsk.hr/urn:nbn:hr:168:619320

D. Babojelić, "Preklapanje visoko pouzdanih jednomolekularnih očitanja", Master's thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:168:619320

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Metadata
TitlePreklapanje visoko pouzdanih jednomolekularnih očitanja
Title (english)Overlapping Single Molecule High-Fidelity Sequencing Data
AuthorDario Babojelić
MentorMile Šikić (mentor)
Committee memberMile Šikić (predsjednik povjerenstva)
Committee memberAna Sović Kržić (član povjerenstva)
Committee memberKrešimir Križanović (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Electrical Engineering and Computing
Zagreb
Defense date and country2020-07-13, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Computing
Abstract
Pacific Biosciences je nedavno predstavio novu tehnologiju za sekvenciranje dugačkih očitanja. Za razliku od dotadašnjih tehnologija za dugačka očitanja, nova jednomolekularna visoko pouzdana tehnologija stvara očitanja visoke točnosti koja se zato nazivaju \textit{HiFi (High-Fidelity)} očitanja. Trenutne metode za analizu DNA očitanja nisu prilagođene za rad nad visoko pouzdanim dugačkim očitanjima. Tema ovog rada je pronalazak novih i nadogradnja starih metoda za pronalazak preklapanja i mapiranja koje će efikasnije koristiti nova visoko pouzdana očitanja.
Abstract (english)
Recently, Pacific Biosciences improved their sequencing chemistry and sequencer performance, which resulted in a novel protocol enabling high-fidelity (HiFi) fragments. These single molecule real-time HiFi reads offer high accuracy while maintaining the length of longer reads. Current state of the art software for analyzing DNA reads were not developed to utilize that. The main subject of this thesis is exploiting the length and accuracy of HiFi reads. New methods, which adapt less sensitive approaches, for finding overlaps and mapping of DNA HiFi reads are explored and tested.
Keywords
Keywords (english)
Languageenglish
URN:NBNurn:nbn:hr:168:619320
Study programmeTitle: Computing
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka računarstva (magistar/magistra inženjer/inženjerka računarstva)
Type of resourceText
File originBorn digital
Access conditionsClosed access
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Created on2023-01-13 11:42:05